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Article

Presenilin expression during induced differentiation of the human neuroblastoma SH-SY5Y cell line.

Neurochemistry international - 1 Jun 2004

Flood Fiona, Sundström Erik, Samuelsson Eva-Britt, Wiehager Birgitta, Seiger Ake, Johnston Janet A, Cowburn Richard F

Abstract excerpt

Human neuroblastoma SH-SY5Y cells stably transfected with both wild-type and exon-9 deleted (deltaE9) presenilin constructs were used to study the role of the presenilin proteins during differentiation. Cells transfected with either wild-type or deltaE9 PS1, of which the latter abolishes normal endoproteolytic cleavage of the protein, showed no obvious differences in their ability to differentiate to a...

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PMID: 15209417
DOI: 10.1016/j.neuint.2003.09.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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