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Article

The presenilin 1 mutation (M146V) linked to familial Alzheimer's disease attenuates the neuronal differentiation of NTera 2 cells.

Biochemical and biophysical research communications - 27 Mar 1998

Tokuhiro S, Tomita T, Iwata H, Kosaka T, Saido T C, Maruyama K, Iwatsubo T

Abstract excerpt

Mutations in presenilin 1 (PS1) gene are the major cause of early-onset familial Alzheimer's disease. The biological functions of PS1 remain elusive, although accumulating evidence suggests that PS1 may play an important role in development and differentiation. To learn about the significance of...

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Identifiers

PMID: 9535737
DOI: 10.1006/bbrc.1998.8336

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-9535737-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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