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Article

A fluorescent probe of polyamine transport accumulates into intracellular acidic vesicles via a two-step mechanism.

The Journal of biological chemistry - 19 Nov 2004

Soulet Denis, Gagnon Bruno, Rivest Serge, Audette Marie, Poulin Richard

Abstract excerpt

Mammalian polyamine carriers have not yet been molecularly identified. The fluoroprobe Spd-C2-BODIPY faithfully reports polyamine transport and accumulates almost exclusively in polyamine-sequestering vesicles (PSVs). Polyamines might thus be imported first by a plasma membrane carrier and then sequestered into pre-existing PSVs (model A), or be directly captured by polyamine receptors undergoing endocytosis...

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PMID: 15208319
DOI: 10.1074/jbc.M401287200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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