Article

Heterocyclic sterol probes for live monitoring of sterol trafficking and lysosomal storage disorders

2018-02-19

Abstract excerpt

The monitoring of intracellular cholesterol homeostasis and trafficking is of great importance because their imbalance leads to many pathologies. Reliable tools for cholesterol detection are in demand. This study presents the design and synthesis of fluorescent probes for cholesterol recognition and demonstrates their selectivity by a variety of methods. The construction of dedicated library of 14 probes was based...

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Literature Corpus work: be8c7939-cdb1-5f85-b17e-55aa5adcce12
DOI: 10.1101/267948

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