Article
The association between panic disorder and the L/L genotype of catechol-O-methyltransferase.
Journal of psychiatric research - 1 Jan 2000
Woo Jong-Min, Yoon Kyung-Sik, Choi Young-Hee, Oh Kang-Sub, Lee Young-Sik, Yu Bum-Hee
Abstract excerpt
To clarify the role of catechol-O-methyltransferase (COMT) polymorphism in panic disorder (PD), we investigated a large group of Korean PD patients (N = 178) and controls (N = 182) using a case-control study. We also assessed the response to paroxetine treatment and other clinical variables in the PD patients. The increase in the COMT(L) allele was not statistically significant in PD (p = 0.104). However,...
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