Article
The COMT L allele modifies the association between MAOB polymorphism and PD in Taiwanese.
Neurology - 13 Feb 2001
Wu R M, Cheng C W, Chen K H, Lu S L, Shan D E, Ho Y F, Chern H D
Abstract excerpt
OBJECTIVE: Reports suggest that catechol-O-methyltransferase (COMT(L/L)) (Val(158)/Met) and monoamine oxidase B (MAOB) intron 13 genotype polymorphism is associated with PD. To understand the ethnicity-specific effects of genetic polymorphism, we performed a case-control study of the association between PD susceptibility and polymorphism of MAOB and COMT, both separately and in combination, in Taiwanese. METHODS:...
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