Article
Gene×gene×gender interaction of BDNF and COMT genotypes associated with panic disorder.
Progress in neuro-psychopharmacology & biological psychiatry - 3 Jun 2014
Konishi Yoshiaki, Tanii Hisashi, Otowa Takeshi, Sasaki Tsukasa, Tochigi Mamoru, Umekage Tadashi, Motomura Eishi, Shiroyama Takashi, Kaiya Hisanobu, Okazaki Yuji, Okada Motohiro
Abstract excerpt
Genetic and gender differences are among the factors that have a role in the etiology of panic disorder (PD). It is thought that PD is related to neurotransmitter pathways, such as brain-derived neurotrophic factor (BDNF) and catechol-O-methyltransferase (COMT), both of which are involved in the regulation of the monoamine mechanism. We examined the interactions of BDNF, COMT and gender differences in terms of...
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