Characterization of two electrophoretic lactate dehydrogenase-A mutants in Mus musculus.

doi:10.1007/BF00554427

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Article

Characterization of two electrophoretic lactate dehydrogenase-A mutants in Mus musculus.

Biochemical genetics - 1 Feb 1992

Merkle S, Pretsch W

Abstract excerpt

Two lactate dehydrogenase (LDH) mutations were recovered independently among offspring of ethylnitrosourea-treated male mice by screening for alterations of isoelectric focusing pattern in liver homogenates. Investigations of physicochemical and kinetic properties of the mutant enzymes indicated...

Topics

Animals
Crosses, Genetic
Erythrocytes
Female
L-Lactate Dehydrogenase
Liver
Male
Mice
Mice, Inbred C3H
Muscles
Mutation
Spleen

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