Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular analysis of four lactate dehydrogenase-A mutants in the mouse.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Dec 1994

Sandulache R, Pretsch W, Chatterjee B, Gimbel W, Graw J, Favor J

Abstract excerpt

Four electrophoretic and/or enzyme-activity variants of murine LDH-A subunit (Ldhla-m1Neu, Ldhla-m5Neu, Ldhla-m6Neu, Ldhla-m9Neu), induced by procarbazine hydrochloride or ethylnitrosourea (ENU), were analyzed at the DNA level. The exons of the Ldhl gene from homozygous mutants were amplified by PCR and sequenced. Three mutations resulted from nucleotide substitutions in exon 5: the transitions A-->G at codons...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Base Sequence

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Mutational Analysis

Share to Homozygote

Share to Molecular Sequence Data

Share to Mutation

Source

Identifiers

PMID: 7534515
DOI: 10.1007/BF00292012

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular analysis of four lactate dehydrogenase-A mutants in the mouse.PMID 7534515Read ↗

Characterization of two electrophoretic lactate dehydrogenase-A mutants in Mus musculus.Semantic proximity Read ↗

Molecular, genetic and biochemical characterization of lactate dehydrogenase-A enzyme activity mutations in Mus musculus.Semantic proximity Read ↗

Hereditary lactate dehydrogenase A-subunit deficiency as cause of early postimplantation death of homozygotes in Mus musculus.Semantic proximity Read ↗

A mutation affecting the lactate dehydrogenase locus Ldh-1 in the mouse. II. Mechanism of the LDH-A deficiency associated with hemolytic anemia.Semantic proximity Read ↗

Molecular characterization of genetic mutation in human lactate dehydrogenase-A (M) deficiency.Semantic proximity Read ↗

Genotypic analysis of families with lactate dehydrogenase A (M) deficiency by selective DNA amplification.Semantic proximity Read ↗

[The mutation units of loci coding for lactate dehydrogenase and their directed changes in the phylogenetic progression of vertebrate animals].Semantic proximity Read ↗

Analysis of mouse hemoglobin alpha-chain locus mutation induced by N-ethyl-N-nitrosourea.Semantic proximity Read ↗

Molecular analysis of genetic mutation in electrophoretic variant of human lactate dehydrogenase-A(M) subunit.Semantic proximity Read ↗

Molecular characterization of genetic mutations in human lactate dehydrogenase (LDH) B (H) variant.Semantic proximity Read ↗

Population screening of lactate dehydrogenase deficiencies in Fukuoka Prefecture in Japan and molecular characterization of three independent mutations in the lactate dehydrogenase-B(H) gene.Semantic proximity Read ↗

Analysis of genetic mutations in human lactate dehydrogenase-A(M) deficiency using DNA conformation polymorphism in combination with polyacrylamide gradient gel and silver staining.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.