Article
Oxidative damage in Huntington's disease.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2004
Segovia José, Pérez-Severiano Francisca
Abstract excerpt
Huntington's disease is a hereditary neurodegenerative disorder, characterized by motor, psychiatric, and cognitive symptoms. The genetic defect responsible for the onset of the disease, expansion of CAG repeats in exon 1 of the gene that codes for huntingtin, has been unambiguously identified. On the other hand, the mechanisms by which the mutation causes the disease are not completely understood yet. However,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
