Article
Free radical damage and oxidative stress in Huntington's disease.
The Journal of the Florida Medical Association - 1 May 1996
Borlongan C V, Kanning K, Poulos S G, Freeman T B, Cahill D W, Sanberg P R
Abstract excerpt
Bioenergetic defects and oxidative stress may be critical links in an excitotoxic mechanism of neuronal death. Oxidative stress, a condition describing the production of oxygen radicals beyond a threshold for proper antioxidant neutralization, has been implicated as a pathologic condition in several neurodegenerative disorders such as Parkinson's disease and Alzheimer's disease. In addition, oxygen radicals are...
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