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Article

Mouse Huntington's disease homolog mRNA levels: variation and allele effects.

Gene expression - 1 Jan 2004

Dixon Karen T, Cearley Jamie A, Hunter Jesse M, Detloff Peter J

Abstract excerpt

Huntington's disease homolog (Hdh) mRNA levels in mice with different Hdh alleles were measured. Brain Hdh mRNA levels varied up to threefold in genetically identical wild-type mice, indicating nongenetic factors influence Hdh expression. Striatal Hdh mRNA levels from an allele with a repeat expanded to 150 CAGs were diminished compared with wild-type and showed variation that might contribute to phenotypic...

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Identifiers

PMID: 15200234
DOI: 10.3727/000000003783992234
PMCID: PMC5991148

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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