Article
Lung cancer susceptibility: are we on our way to identifying a high-risk group?
Future oncology (London, England) - 1 Dec 2007
Kiyohara Chikako, Yoshimasu Kouichi, Takayama Koichi, Nakanishi Yoichi
Abstract excerpt
Many studies have investigated lung cancer susceptibility based on the presence of low-penetrance, high-frequency single nucleotide polymorphisms. Identifying such susceptibility polymorphisms may lead to the development of tests that allow a more focused follow-up of a high-risk group. Genetic polymorphisms of xenobiotic metabolism, DNA repair, cell-cycle control, immunity, addiction and nutritional status have...
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