Article
Evaluation of the role of Nurr1 in a large sample of familial Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society - 1 Jun 2004
Nichols William C, Uniacke Sean K, Pankratz Nathan, Reed Terry, Simon David K, Halter Cheryl, Rudolph Alice, Shults Clifford W, Conneally P Michael, Foroud Tatiana
Abstract excerpt
Parkinson's disease (PD) is a common neurodegenerative disorder in humans with wide variability in the age of disease onset. Although the disease has been thought previously to occur sporadically in most patients, there is increasing evidence of a genetic contribution to the disorder. Recently, a polymorphic variant within intron 6 of the Nurr1 gene was reported to be associated with sporadic and familial PD. In...
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