Article
Absence of previously reported variants in the SCNA (G88C and G209A), NR4A2 (T291D and T245G) and the DJ-1 (T497C) genes in familial Parkinson's disease from the GenePD study.
Movement disorders : official journal of the Movement Disorder Society - 1 Sept 2005
Karamohamed Samer, Golbe L I, Mark M H, Lazzarini A M, Suchowersky O, Labelle N, Guttman Mark, Currie L J, Wooten G F, Stacy M, Saint-Hilaire M, Feldman R G, Liu J, Shoemaker C M, Wilk J B, DeStefano A L, Latourelle J C, Xu G, Watts R, Growdon J, Lew M, Waters C, Vieregge P, Pramstaller P P, Klein C, Racette B A, Perlmutter J S, Parsian A, Singer Carlos, Montgomery E, Baker K, Gusella J F, Herbert A, Myers R H
Abstract excerpt
Parkinson's disease (PD) is a neurodegenerative disorder in which relatives of the probands are affected approximately 4 times as frequently as relatives of control subjects. Several genes have been implicated as genetic risk factors for PD. We investigated the presence of six reported genetic variations in the SCNA, NR4A2, and DJ-1 genes in 292 cases of familial Parkinson's disease from the GenePD study. None of...
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