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Article

Association of homozygous 7048G7049 variant in the intron six of Nurr1 gene with Parkinson's disease.

Neurology - 26 Mar 2002

Xu P-Y, Liang R, Jankovic J, Hunter C, Zeng Y-X, Ashizawa T, Lai D, Le W-D

Abstract excerpt

OBJECTIVE: To determine whether the Nurr1 gene, which is critical for the development and maintenance of nigral dopaminergic neurons, is a risk factor associated with PD. BACKGROUND: The Nurrl gene is highly expressed in the dopaminergic neurons in the midbrain. Knockout of the gene results in agenesis of nigral dopaminergic neurons and heterozygous knockout mice increases...

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Identifiers

PMID: 11914402
DOI: 10.1212/wnl.58.6.881

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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