Article
A common NURR1 polymorphism associated with Parkinson disease and diffuse Lewy body disease.
Archives of neurology - 1 May 2003
Zheng Kangni, Heydari Bobak, Simon David K
Abstract excerpt
BACKGROUND: NURR1 plays a key role in mesencephalic dopaminergic neuron development and survival. A homozygous NURR1 polymorphism (a single base-pair insertion in intron 6) (NI6P) has been reported to be associated with Parkinson disease (PD). OBJECTIVE: To assess the association of the NI6P with...
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