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Article

Ex vivo phenotype and frequency of influenza virus-specific CD4 memory T cells.

Journal of virology - 1 Jul 2004

Lucas Michaela, Day Cheryl L, Wyer Jessica R, Cunliffe Sharon L, Loughry Andrew, McMichael Andrew J, Klenerman Paul

Abstract excerpt

Recent advances in class II tetramer staining technology have allowed reliable direct ex vivo visualization of antigen-specific CD4 T cells. In order to define the frequency and phenotype of a prototype response to a nonpersistent pathogen, we have used such techniques to analyze influenza virus-specific memory CD4 T cells directly from blood. These responses are stably detectable ex vivo at low frequencies...

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Share to CD4-Positive T-Lymphocytes
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15194806
DOI: 10.1128/JVI.78.13.7284-7287.2004
PMCID: PMC421690

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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