Article
[A HLA-A2-restricted-CTL epitope variation at the N-terminal of HCV helicase and the immune response of CTLs].
Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology - 1 May 2004
Guo Hua-zhang, Wang Wen-liang, Wang Tao
Abstract excerpt
AIM: To investigate a HLA-A2-restricted CTL epitope variation at the N terminal of hepatitis C virus (HCV) helicase and the proliferative response of cytotoxic T lymphocytes (CTLs) to this epitope. METHODS: Two patients infected with HCV were followed up for 7 years. Blood samples taken at the first year and the fifth year were used for viral RNA extraction. Using RT-PCR, the N terminal gene of helicase region...
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