Article
Three new cytotoxic T cell epitopes identified within the hepatitis C virus nucleoprotein.
The Journal of general virology - 1 Jun 1996
Kaneko T, Nakamura I, Kita H, Hiroishi K, Moriyama T, Imawari M
Abstract excerpt
Cytotoxic T lymphocytes (CTLs) may play a role in host defence against hepatitis C virus (HCV) infection, and HCV-specific CTL epitopes may be included in vaccines to induce protective CTLs. We identified three new epitopes within the HCV nucleoprotein recognized by CTLs. HCV nucleoprotein residues 28-37 are the minimal epitope recognized by CTLs in association with the class I human leukocyte antigen B60, and...
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