Article
A peptide derived from hepatitis C virus (HCV) core protein inducing cellular responses in patients with HCV with various HLA class IA alleles.
Journal of medical virology - 1 Jul 2009
Niu Yamei, Komatsu Nobukazu, Komohara Yoshihiro, Matsueda Satoko, Yutani Shigeru, Ishihara Yuki, Itou Minoru, Yamada Akira, Itoh Kyogo, Shichijo Shigeki
Abstract excerpt
C35-44 peptide is a well known HLA-A2-restricted CTL epitope originating from hepatitis C virus (HCV) core protein. It was reported that the majority of HCV positive patients had significant levels of serum IgG specific to this peptide. This study addressed whether C35-44 peptide could induce CTL activity restricted to various HLA class IA alleles or could not. This peptide demonstrated binding activity to...
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