Article
Identification of HLA-A3 and -B7-restricted CTL response to hepatitis C virus in patients with acute and chronic hepatitis C.
Journal of immunology (Baltimore, Md. : 1950) - 15 Jan 1999
Chang K M, Gruener N H, Southwood S, Sidney J, Pape G R, Chisari F V, Sette A
Abstract excerpt
The inverse relationship between peripheral blood CTL responsiveness to multiple hepatitis C virus (HCV) epitopes and viral titer in patients with persistent HCV infection suggests that enhancement of the CTL response might result in viral clearance. Since several HLA-A2-restricted HCV CTL epitopes are already known, we aimed to identify CTL epitopes restricted by other HLA types in an effort to expand the...
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