Article
Sequence evolution of putative cytotoxic T cell epitopes in NS3 region of hepatitis C virus.
World journal of gastroenterology - 15 Mar 2004
Guo Hua-Zhang, Yin Ying, Wang Wen-Liang, Zhang Chuan-Shan, Wang Tao, Wang Zhe, Zhang Jing, Cheng Hong, Wang Hai-Tao
Abstract excerpt
AIM: Quasispecies of hepatitis C virus (HCV) are the foundation for rapid sequence evolution of HCV to evade immune surveillance of hosts. The consensus sequence evolution of a segment of HCV NS3 region, which encompasses putative cytotoxic T cell epitopes, was evaluated. METHODS: Three male patients, infected with HCV through multiple transfusions, were identified from clinical symptoms and monitored by...
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