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Article

Transgenic mice overexpressing amyloid beta protein are an incomplete model of Alzheimer disease.

Experimental neurology - 1 Jul 2004

Schwab Claudia, Hosokawa Masato, McGeer Patrick L

Abstract excerpt

We compared lesions in elderly transgenic (tg) mice carrying the Swedish double mutation KM670/671NL with lesions in Alzheimer disease (AD) by histochemical and immunohistochemical techniques. Highly similar staining for beta-amyloid protein (Abeta) was observed in AD and the mouse models. The abundant amyloid deposits in tg mice were in a consolidated state as revealed by strong Congo red birefringence. In both...

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PMID: 15191802
DOI: 10.1016/j.expneurol.2004.03.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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