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Article

A psoriasis vulgaris protective gene maps close to the HLA-C locus on the EH18.2-extended haplotype.

Tissue antigens - 1 Jul 2004

Contu L, Orrù S, Carcassi C, Giuressi E, Mulargia M, Cappai L, Valentini D, Lai S, Boero R, Masala M V, Aste N, Biggio P, Cottoni F, Cerimele D

Abstract excerpt

We determined the molecular haplotypes of the HLA-A, HLA-C and HLA-B loci and the MHC class I-B-related (MIB) microsatellite in 179 unrelated psoriatic patients (72 familial cases) and in 120 controls. The HLA-A*3002-Cw*0501-B*1801-MIB1 haplotype showed a strong negative association with psoriasis vulgaris (PV) and in particular with familial PV, revealing the presence of a PV-protective gene. Analysis of...

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Source

Identifiers

PMID: 15191522
DOI: 10.1111/j.1399-0039.2004.00235.x

Genes

MIB1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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