Article
Comparative association analysis reveals that corneodesmosin is more closely associated with psoriasis than HLA-Cw*0602-B*5701 in German families.
Tissue antigens - 1 May 2001
Schmitt-Egenolf M, Windemuth C, Hennies H C, Albis-Camps M, von Engelhardt B, Wienker T, Reis A, Traupe H, Blasczyk R
Abstract excerpt
HLA antigens are associated with psoriasis vulgaris across populations with different ethnic background. We have previously shown that in Caucasians this association is primarily based on the class I alleles of the extended HLA haplotype 57.1 (EH57.1/I), HLA-Cw6-HLA-B57. However, it remained unclear whether HLA-Cw6 itself or a closely linked locus predisposes to the disease. An interesting candidate for this...
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