Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Localization of psoriasis-susceptibility locus PSORS1 to a 60-kb interval telomeric to HLA-C.

American journal of human genetics - 1 Jun 2000

Nair R P, Stuart P, Henseler T, Jenisch S, Chia N V, Westphal E, Schork N J, Kim J, Lim H W, Christophers E, Voorhees J J, Elder J T

Abstract excerpt

Recent genome scans have established the presence of a major psoriasis-susceptibility locus in the human leukocyte antigen (HLA) complex on chromosome 6p21.3. To narrow the interval for candidate gene testing, we performed a linkage-disequilibrium analysis of 339 families, with the use of 62 physically mapped microsatellite markers spanning the major histocompatibility complex (MHC). As detected by use of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomes, Human, Pair 6
Share to Gene Order

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glycoproteins

Share to HLA-C Antigens

Share to Intercellular Signaling Peptides and Proteins

Share to Likelihood Functions

Share to Psoriasis

Share to Telomere

Source

Open in PubMed Open full text

Identifiers

PMID: 10801386
DOI: 10.1086/302932
PMCID: PMC1378062

Genes

MICA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Localization of psoriasis-susceptibility locus PSORS1 to a 60-kb interval telomeric to HLA-C.PMID 10801386Read ↗

Sequence and haplotype analysis supports HLA-C as the psoriasis susceptibility 1 gene.Semantic proximity Read ↗

Family-based analysis using a dense single-nucleotide polymorphism-based map defines genetic variation at PSORS1, the major psoriasis-susceptibility locus.Semantic proximity Read ↗

Mapping of the major psoriasis-susceptibility locus (PSORS1) in a 70-Kb interval around the corneodesmosin gene (CDSN).Semantic proximity Read ↗

Searching for the major histocompatibility complex psoriasis susceptibility gene.Semantic proximity Read ↗

Localization of PSORS1 to a haplotype block harboring HLA-C and distinct from corneodesmosin and HCR.Semantic proximity Read ↗

An in-depth characterization of the major psoriasis susceptibility locus identifies candidate susceptibility alleles within an HLA-C enhancer element.Semantic proximity Read ↗

Fine mapping of the psoriasis susceptibility gene PSORS1: a reassessment of risk associated with a putative risk haplotype lacking HLA-Cw6.Semantic proximity Read ↗

Characterization of the major susceptibility region for psoriasis at chromosome 6p21.3.Semantic proximity Read ↗

Fine mapping of the PSORS4 psoriasis susceptibility region on chromosome 1q21.Semantic proximity Read ↗

The genetic basis of psoriasis.Semantic proximity Read ↗

Fine mapping of the psoriasis susceptibility locus PSORS1 supports HLA-C as the susceptibility gene in the Han Chinese population.Semantic proximity Read ↗

Characterisation of psoriasis susceptibility locus 6 (PSORS6) in patients with early onset psoriasis and evidence for interaction with PSORS1.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.