Article
RBR1, a novel pH-regulated cell wall gene of Candida albicans, is repressed by RIM101 and activated by NRG1.
Eukaryotic cell - 1 Jun 2004
Lotz Henrike, Sohn Kai, Brunner Herwig, Muhlschlegel Fritz A, Rupp Steffen
Abstract excerpt
The transcription factor Rim101p of Candida albicans has been shown to play a major role in pH-dependent gene regulation. Rim101p is involved in cell wall biosynthesis, since it regulates PHR1 and PHR2, two almost functionally redundant cell wall glycosidases important for adaptation to either neutral or acidic habitats within the human host. To identify additional cell wall components regulated by Rim101p, we...
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