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Article

Evidence for novel pH-dependent regulation of Candida albicans Rim101, a direct transcriptional repressor of the cell wall beta-glycosidase Phr2.

Eukaryotic cell - 1 Sept 2006

Baek Yong-Un, Martin Samuel J, Davis Dana A

Abstract excerpt

Candida albicans is a commensal fungus of mucosal surfaces that can cause disease in susceptible hosts. One aspect of the success of C. albicans as both a commensal and a pathogen is its ability to adapt to diverse environmental conditions, including dramatic variations in environmental pH. The response to a neutral-to-alkaline pH change is controlled by the Rim101 signal transduction pathway. In...

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Identifiers

PMID: 16963637
DOI: 10.1128/EC.00088-06
PMCID: PMC1563585

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Evidence for novel pH-dependent regulation of Candida albicans Rim101, a direct transcriptional repressor of the cell wall beta-glycosidase Phr2.PMID 16963637Read ↗

RBR1, a novel pH-regulated cell wall gene of Candida albicans, is repressed by RIM101 and activated by NRG1.Semantic proximity Read ↗

RIM101-dependent and-independent pathways govern pH responses in Candida albicans.Semantic proximity Read ↗

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Malassezia responds to environmental pH signals through the conserved Rim/Pal pathwaySemantic proximity Read ↗

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Diverged binding specificity of Rim101p, the Candida albicans ortholog of PacC.Semantic proximity Read ↗

Dominant active alleles of RIM101 (PRR2) bypass the pH restriction on filamentation of Candida albicans.Semantic proximity Read ↗

The Cryptococcus neoformans Rim101 Transcription Factor Directly Regulates Genes Required for Adaptation to the HostSemantic proximity Read ↗

<i>Candida albicans</i>transcription factor Rim101 mediates pathogenic interactions through cell wall functionsSemantic proximity Read ↗

Transcriptional expression of PHR2 is positively controlled by the calcium signaling transcription factor Crz1 through its binding motif in the promoterSemantic proximity Read ↗

pH Response Pathways in Fungi: Adapting to Host-derived and Environmental SignalsSemantic proximity Read ↗

The transcription factor Rim101p governs ion tolerance and cell differentiation by direct repression of the regulatory genes NRG1 and SMP1 in Saccharomyces cerevisiae.Semantic proximity Read ↗

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