Article
Diverged binding specificity of Rim101p, the Candida albicans ortholog of PacC.
Eukaryotic cell - 1 Aug 2003
Ramón Ana M, Fonzi William A
Abstract excerpt
The biology of Candida albicans, including dimorphism and virulence, is significantly influenced by environmental pH. The response to ambient pH includes the pH-conditional expression of several genes, which is directly or indirectly regulated by Rim101p. Rim101p is homologous to PacC, a transcription factor that regulates pH-conditional gene expression in Aspergillus nidulans. PacC binds 5'-GCCARG-3' sequences...
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