Article
PHR1, a pH-regulated gene of Candida albicans, is required for morphogenesis.
Molecular and cellular biology - 1 Feb 1995
Saporito-Irwin S M, Birse C E, Sypherd P S, Fonzi W A
Abstract excerpt
Candida albicans, like many fungi, exhibits morphological plasticity, a property which may be related to its biological capacity as an opportunistic pathogen of humans. Morphogenesis and alterations in cell shape require integration of many cellular functions and occur in response to environmental signals, most notably pH and temperature in the case of C. albicans. In the course of our studies of differential...
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