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Article

The electrostatic nature of C3d-complement receptor 2 association.

Journal of immunology (Baltimore, Md. : 1950) - 15 Jun 2004

Morikis Dimitrios, Lambris John D

Abstract excerpt

The association of complement component C3d with B or T cell complement receptor 2 (CR2 or CD21) is a link between innate and adaptive immunity. It has been recognized in experimental studies that the C3d-CR2 association is pH- and ionic strength-dependent. This led us to perform electrostatic calculations to obtain a theoretical understanding of the mechanism of C3d-CR2 association. We used the crystallographic...

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Identifiers

PMID: 15187133
DOI: 10.4049/jimmunol.172.12.7537

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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