Article
Electrostatic Steering Accelerates C3d:CR2 Association.
The journal of physical chemistry. B - 25 Aug 2016
Mohan Rohith R, Huber Gary A, Morikis Dimitrios
Abstract excerpt
Electrostatic effects are ubiquitous in protein interactions and are found to be pervasive in the complement system as well. The interaction between complement fragment C3d and complement receptor 2 (CR2) has evolved to become a link between innate and adaptive immunity. Electrostatic interactions have been suggested to be the driving factor for the association of the C3d:CR2 complex. In this study, we...
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