Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Solvation effects in calculated electrostatic association free energies for the C3d-CR2 complex and comparison with experimental data.

Biopolymers - 1 Jun 2010

Cheung Alexander S, Kieslich Chris A, Yang Jianfeng, Morikis Dimitrios

Abstract excerpt

The complement system is an integral part of the innate immune system that participates in the clearance of pathogens from the body. The association between complement protein fragment C3d and B or T cell-receptor complement receptor (CR) 2 represents a crucial link between innate and adaptive immunities. The goal of this study is to predict association abilities of C3d and CR2 mutants by theoretically...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biotechnology
Share to Chemistry, Physical

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Complement System Proteins

Share to Immune System

Share to Molecular Conformation

Share to Receptors, Complement 3d

Share to Solvents

Share to Static Electricity

Source

Identifiers

PMID: 20091675
DOI: 10.1002/bip.21388

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Solvation effects in calculated electrostatic association free energies for the C3d-CR2 complex and comparison with experimental data.PMID 20091675Read ↗

The electrostatic nature of C3d-complement receptor 2 association.Semantic proximity Read ↗

Electrostatic Steering Accelerates C3d:CR2 Association.Semantic proximity Read ↗

Automated computational framework for the analysis of electrostatic similarities of proteins.Semantic proximity Read ↗

Ionic tethering contributes to the conformational stability and function of complement C3b.Semantic proximity Read ↗

Energetic evaluation of binding modes in the C3d and Factor H (CCP 19-20) complex.Semantic proximity Read ↗

Inferring the microscopic surface energy of protein-protein interfaces from mutation data.Semantic proximity Read ↗

Insights into the role of C3d dimers in B cell activation and Staphylococcal immune evasionSemantic proximity Read ↗

Molecular dynamics simulations of wild type and mutants of human complement receptor 2 complexed with C3dSemantic proximity Read ↗

X-ray crystal structure of C3d: a C3 fragment and ligand for complement receptor 2.Semantic proximity Read ↗

Alchemical Calculation of Relative Free Energies for Charge-Changing Mutations at Protein-Protein Interfaces Considering Fixed and Variable Protonation States.Semantic proximity Read ↗

New hypotheses about the structure-function of proprotein convertase subtilisin/kexin type 9: analysis of the epidermal growth factor-like repeat A docking site using WaterMap.Semantic proximity Read ↗

Stacking interactions between carbohydrate and protein quantified by combination of theoretical and experimental methods.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.