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Article

X-ray crystal structure of C3d: a C3 fragment and ligand for complement receptor 2.

Science (New York, N.Y.) - 22 May 1998

Nagar B, Jones R G, Diefenbach R J, Isenman D E, Rini J M

Abstract excerpt

Activation and covalent attachment of complement component C3 to pathogens is the key step in complement-mediated host defense. Additionally, the antigen-bound C3d fragment interacts with complement receptor 2 (CR2; also known as CD21) on B cells and thereby contributes to the initiation of an acquired humoral response. The x-ray crystal structure of human C3d solved at 2.0 angstroms resolution reveals an...

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Identifiers

PMID: 9596584
DOI: 10.1126/science.280.5367.1277

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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