Article
The increase in cholesterol with menopause is associated with the apolipoprotein E genotype. A population-based longitudinal study.
Atherosclerosis - 1 Jul 2004
Hak A Elisabeth, Witteman Jacqueline C M, Hugens Wendy, Keyzer Jules J, Pop Victor J, Uitterlinden André G, Pols Huibert A P
Abstract excerpt
During menopause, a sharp increase in cholesterol concentration occurs with an unexplained wide variation in change. Possibly, this is attributable to genetic variation. The authors prospectively studied the effect of the apolipoprotein E (APOE) genotype on the change in cholesterol level with menopause among 1116 Dutch women. Women with the APOE3E3 genotype were regarded as the reference category and changes...
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