Article
Sex-specific interaction between APOE and APOA5 variants and determination of plasma lipid levels.
European journal of human genetics : EJHG - 1 Jan 2008
Hubacek Jaroslav A, Lánská Vera, Skodová Zdena, Adámková Vera, Poledne Rudolf
Abstract excerpt
The APOA5 and APOE genes play an important role in determination of plasma levels of triglycerides (TG) and total cholesterol (TC). We have analyzed APOA5 (T-1131>C and Ser19>Trp) and APOE (e2/e3/e4) variants in 2500 representatively selected Caucasians (1168 men, 1332 women). In female subjects (but not in male) an association between APOE polymorphism and TC was observed on the background of the common APOA5...
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