Article
Evidence that the apolipoprotein E-genotype effects on lipid levels can change with age in males: a longitudinal analysis.
American journal of human genetics - 1 Jul 1997
Jarvik G P, Goode E L, Austin M A, Auwerx J, Deeb S, Schellenberg G D, Reed T
Abstract excerpt
We previously reported that change, with age, in plasma levels of total cholesterol (TC) and LDL cholesterol (LDL-C) differed between apolipoprotein E (APOE) genotypes epsilon 3 epsilon 3 and epsilon 3 epsilon 4, in a sample of 77 older, unrelated males. By use of a larger sample from that cohort, followed longitudinally during 1969-87, the change in TC and in LDL-C, between the epsilon 3 epsilon 3 and epsilon 3...
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