Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Apolipoprotein E (ApoE) polymorphism is related to differences in potential fertility in women: a case of antagonistic pleiotropy?

Proceedings. Biological sciences - 22 Mar 2015

Jasienska Grazyna, Ellison Peter T, Galbarczyk Andrzej, Jasienski Michal, Kalemba-Drozdz Malgorzata, Kapiszewska Maria, Nenko Ilona, Thune Inger, Ziomkiewicz Anna

Abstract excerpt

The alleles that are detrimental to health, especially in older age, are thought to persist in populations because they also confer some benefits for individuals (through antagonistic pleiotropy). The ApoE4 allele at the ApoE locus, encoding apolipoprotein E (ApoE), significantly increases risk of poor health, and yet it is present in many populations at relatively high frequencies. Why has it not been replaced...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apolipoprotein E3
Share to Apolipoprotein E4

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Fertility

Share to Genetic Pleiotropy

Share to Menstrual Cycle

Share to Progesterone

Share to Reproduction

Share to Saliva

Source

Open in PubMed Open full text

Identifiers

PMID: 25673673
DOI: 10.1098/rspb.2014.2395
PMCID: PMC4345437

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Apolipoprotein E (ApoE) polymorphism is related to differences in potential fertility in women: a case of antagonistic pleiotropy?PMID 25673673Read ↗

Apolipoprotein E Polymorphism and Reproductive Patterns Among Postreproductive Women.Semantic proximity Read ↗

Study on a possible effect of four longevity candidate genes (ACE, PON1, PPAR-gamma, and APOE) on human fertility.Semantic proximity Read ↗

The Apolipoprotein E Antagonistic Pleiotropy Hypothesis: Review and RecommendationsSemantic proximity Read ↗

Evidence for the role of selection for reproductively advantageous alleles in human aging.Semantic proximity Read ↗

Apolipoprotein E gene determines serum testosterone and dehydroepiandrosterone levels in postmenopausal women.Semantic proximity Read ↗

Evidence for the role of selection for reproductively advantageous alleles in human agingSemantic proximity Read ↗

Apolipoprotein E polymorphism and fertility: a study in pre-industrial populations.Semantic proximity Read ↗

ApoE genotype: impact on health, fitness and nutrition.Semantic proximity Read ↗

Are apolipoprotein E alleles correlated with semen quality?Semantic proximity Read ↗

The Role of ApoE Expression and Variability of Its Glycosylation in Human Reproductive Health in the Light of Current InformationSemantic proximity Read ↗

Effect of APOE ε4 allele on survival and fertility in an adverse environment.Semantic proximity Read ↗

APOE-E4 allele as a potential marker for implantation failure: A comparison between fertile women, ART success and RIF patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.