Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Lipoprotein processing is required for virulence of Mycobacterium tuberculosis†

21 May 2004

Abstract excerpt

Lipoproteins are a subgroup of secreted bacterial proteins characterized by a lipidated N-terminus, processing of which is mediated by the consecutive activity of prolipoprotein diacylglyceryl transferase (Lgt) and lipoprotein signal peptidase (LspA). The study of LspA function has been limited mainly to non-pathogenic microorganisms. To study a potential role for LspA in the pathogenesis of bacterial infections,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Diagnosis and treatment of tuberculosis
Share to Mycobacterium research and diagnosis
Share to Tuberculosis Research and Epidemiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15186407
DOI: 10.1111/j.1365-2958.2004.04041.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Lipoprotein processing is required for virulence of Mycobacterium tuberculosis†PMID 15186407Read ↗

Lipoproteins ofMycobacterium tuberculosis: an abundant and functionally diverse class of cell envelope componentsSemantic proximity Read ↗

Cell Envelope Lipids in the Pathophysiology of Mycobacterium TuberculosisSemantic proximity Read ↗

Recent advances in deciphering the contribution of Mycobacterium tuberculosis lipids to pathogenesisSemantic proximity Read ↗

FasR regulates fatty acid biosynthesis and is essential for virulence of <i>Mycobacterium tuberculosis</i>Semantic proximity Read ↗

Functional Role of the PE Domain and Immunogenicity of the <i>Mycobacterium tuberculosis</i> Triacylglycerol Hydrolase LipYSemantic proximity Read ↗

Revisiting the role of phospholipases C in virulence and the lifecycle of Mycobacterium tuberculosisSemantic proximity Read ↗

Peptidoglycan synthesis in <i>Mycobacterium tuberculosis</i> is organized into networks with varying drug susceptibilitySemantic proximity Read ↗

Inactivation of Lgt allows systematic characterization of lipoproteins from Listeria monocytogenes.Semantic proximity Read ↗

Lipid metabolism and Type VII secretion systems dominate the genome scale virulence profile of Mycobacterium tuberculosis in human dendritic cells.Semantic proximity Read ↗

Cholesterol-dependent transcriptome remodeling reveals new insight into the contribution of cholesterol to Mycobacterium tuberculosis pathogenesisSemantic proximity Read ↗

Lipid hydrolizing enzymes in virulence:<i>Mycobacterium tuberculosis</i>as a model systemSemantic proximity Read ↗

Characterization of key enzymes involved in triacylglycerol biosynthesis in mycobacteria.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.