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Revisiting the role of phospholipases C in virulence and the lifecycle of Mycobacterium tuberculosis

25 Nov 2015

Abstract excerpt

Mycobacterium tuberculosis, the agent of human tuberculosis has developed different virulence mechanisms and virulence-associated tools during its evolution to survive and multiply inside the host. Based on previous reports and by analogy with other bacteria, phospholipases C (PLC) of M. tuberculosis were thought to be among these tools. To get deeper insights into the function of PLCs, we investigated their...

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PMID: 26603639
DOI: 10.1038/srep16918

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