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Article

Polarized type 1 cytokine response and cell-mediated immunity determine genetic resistance to mousepox.

Proceedings of the National Academy of Sciences of the United States of America - 15 Jun 2004

Chaudhri Geeta, Panchanathan Vijay, Buller R Mark L, van den Eertwegh Alfons J M, Claassen Eric, Zhou Jie, de Chazal Rosalind, Laman Jon D, Karupiah Gunasegaran

Abstract excerpt

Ectromelia virus (ECTV), a natural mouse pathogen and an orthopoxvirus, has been used to investigate the correlation between polarized type 1 or type 2 immune responses and resistance to disease in poxvirus infections by using well defined resistant and susceptible mouse strains. Our data show that distinct differences exist in the cytokine profiles expressed in resistant and susceptible mice infected with ECTV....

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Identifiers

PMID: 15184649
DOI: 10.1073/pnas.0402949101
PMCID: PMC428472

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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