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Article

Obligatory Requirement for Antibody in Recovery from a Primary Poxvirus Infection

15 Jun 2006

Abstract excerpt

To understand the correlates of protective immunity against primary variola virus infection in humans, we have used the well-characterized mousepox model. This is an excellent surrogate small-animal model for smallpox in which the disease is caused by infection with the closely related orthopoxvirus, ectromelia virus. Similarities between the two infections include virus replication and transmission, aspects of...

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PMID: 16775322
DOI: 10.1128/jvi.00116-06

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