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Article

Dosage-dependent functions of fatty acid desaturase Ole1p in growth and morphogenesis of Candida albicans.

Microbiology (Reading, England) - 1 Jun 2004

Krishnamurthy Shankarling, Plaine Armêl, Albert Juliane, Prasad Tulika, Prasad Rajendra, Ernst Joachim F

Abstract excerpt

Conditions in the infected human host trigger virulence attributes of the fungal pathogen Candida albicans. Specific inducers and elevated temperatures lead to hyphal development or regulate chlamydospore development. To explore if these processes are affected by membrane lipids, an investigation of the functions of the Ole1 fatty acid desaturase (stearoyl-CoA desaturase) in C. albicans, which synthesizes oleic...

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PMID: 15184585
DOI: 10.1099/mic.0.27029-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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