Article
Sterol synthesis and viability of erg11 (cytochrome P450 lanosterol demethylase) mutations in Saccharomyces cerevisiae and Candida albicans.
Lipids - 1 Nov 1993
Bard M, Lees N D, Turi T, Craft D, Cofrin L, Barbuch R, Koegel C, Loper J C
Abstract excerpt
The identification of the precise structural features of yeast sterol molecules required for the essential "sparking" function has been a controversial area of research. Recent cloning and gene disruption studies in Saccharomyces cerevisiae have shown that C-24 methylation (ERG6), C-5 desaturatio...
Topics
- Aerobiosis
- Candida albicans
- Cell Division
- Cycloheximide
- Cytochrome P-450 Enzyme System
- Genes, Fungal
- Genes, Suppressor
- Mutation
- Oxidoreductases
- Saccharomyces cerevisiae
- Sterol 14-Demethylase
- Sterols
- Transformation, Genetic