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Article

c-FLIP expression in bladder urothelial carcinomas: its role in resistance to Fas-mediated apoptosis and clinicopathologic correlations.

Urology - 1 Jun 2004

Korkolopoulou Penelope, Goudopoulou Athina, Voutsinas Gerassimos, Thomas-Tsagli Euphemia, Kapralos Panagiotis, Patsouris Efstratios, Saetta Angelica A

Abstract excerpt

OBJECTIVES: To investigate the incidence of Fas (exon 9) mutations and the expression of Fas, Fas-Fas ligand (FasL) system, and cellular FLICE-like inhibitory protein (c-FLIP) in relation to standard clinicopathologic parameters and patient outcome in bladder carcinoma. Disruption of apoptotic cell death has been implicated in tumor aggressiveness in bladder urothelial carcinomas. The FasL system is involved in...

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Identifiers

PMID: 15183989
DOI: 10.1016/j.urology.2004.01.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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