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Article

BH3 domain mutation of proapoptotic genes Bad, Bmf and Bcl-G is rare in transitional cell carcinomas of the urinary bladder.

Pathology - 1 Feb 2006

Soung Young Hwa, Lee Jong Woo, Park Won Sang, Nam Suk Woo, Lee Jung Young, Yoo Nam Jin, Lee Sug Hyung

Abstract excerpt

AIMS: Mounting evidence indicates that deregulation of apoptosis contributes to the development of human cancers. Bcl-2 family proteins regulate the intrinsic apoptosis pathway. The aim of this study was to explore the possibility that mutation of BH3 domain of proapoptotic Bcl-2 genes Bad, Bmf and Bcl-G might be involved in the development of urinary bladder cancer. METHODS: We analysed the BH3 domains of Bad,...

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Share to Adaptor Proteins, Signal Transducing
Share to bcl-Associated Death Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to BH3 Interacting Domain Death Agonist Protein

Share to Carcinoma, Transitional Cell

Share to DNA, Neoplasm

Share to Polymorphism, Single-Stranded Conformational

Share to Proto-Oncogene Proteins c-bcl-2

Share to Urinary Bladder Neoplasms

Source

Identifiers

PMID: 16484005
DOI: 10.1080/00313020500455811

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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