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Article

The Src signaling pathway: a potential target in melanoma and other malignancies

7 Dec 2006

Abstract excerpt

Although Src was the first oncogene to be discovered as the transforming protein of the Rous sarcoma virus almost three decades ago, the role of Src and the Src family kinases in human oncogenesis is still not completely understood. Recent studies have shown that Src regulates cell adhesion, invasiveness and motility in cancer cells and in tumor vasculature, rather than directly influencing cell replication. The...

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PMID: 17150037
DOI: 10.1517/14728222.11.1.91

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