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Article

Src Family Kinases: Potential Targets for the Treatment of Human Cancer and Leukemia

1 Oct 2003

Abstract excerpt

The inherited or acquired deregulation of protein kinase activity has been implicated in the pathogenesis of many human diseases, including cancer. Therefore, the inhibition of kinases has been proposed to be a promising strategy in the context of anti-cancer treatment. Many other kinases have been selected as drug discovery targets based on the prevalence of mutations, over-expression and unscheduled activation...

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PMID: 14529415
DOI: 10.2174/1381612033454126

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