Article
Functional characterization of highly purified human hematopoietic repopulating cells isolated according to aldehyde dehydrogenase activity.
Blood - 15 Sept 2004
Hess David A, Meyerrose Todd E, Wirthlin Louisa, Craft Timothy P, Herrbrich Phillip E, Creer Michael H, Nolta Jan A
Abstract excerpt
Human hematopoietic stem cells (HSCs) are commonly purified by the expression of cell surface markers such as CD34. Because cell phenotype can be altered by cell cycle progression or ex vivo culture, purification on the basis of conserved stem cell function may represent a more reliable way to isolate various stem cell populations. We have purified primitive HSCs from human umbilical cord blood (UCB) by lineage...
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